Saturday, June 12, 2010

Monoclonal Antibodies

The monoclonal antibodies have very hard to remember names. These probably aren't very high yield for the USMLE Step 1, but it may be useful to be able to identify them. Hopefully these mnemonics will help. There are so many monoclonal bodies that have clinical uses, however I'm only going to list the ones that are in the Kaplan Pharmacology Lecture Notes.

  • ABciximab: antagonist of IIb/IIIa receptors (antiplatelet)
  • INFliximab: binds TNF (Rheumatoid arthritis and Crohn disease)
  • TASTtuzumab: ERB-B2 antagonist (breAST cancer)
  • PaliVIzumab: blocks respiratory syntycial VIrus
 The 2 Mabs used in immunosuppression are: (no mnemonic for these)
  • Dacliximab: transplants (IL-2 receptor antagonist)
  • Muromonab: transplants (CD3 antagonist)

2 comments:

  1. Baciliximab is also IL-2 antagonist.

    ReplyDelete
  2. This site is very informative for us which provides lot of information about Monoclonal Antibodies. Thanks for providing me this type of information.
    Monoclonal Antibodies

    ReplyDelete