Wednesday, April 14, 2010

Mannitol (First Aid VS Kaplan)


Kaplan says: Mannitol is used in anuric states

First Aid says: Mannitol is contraindicated in anuria
Which is right? They're both right. Huh? It depends on the cause of anuria. Here is what the ultimate encyclopedia of medicine (wikipedia) says:
"Mannitol is a medicine that is used to increase the amount of water removed from the blood and thus improve the blood flow to the kidneys. However, mannitol is contraindicated in anuria secondary to renal disease, severe dehydration, intracranial bleeding (unless during craniotomy), severe pulmonary congestion, or pulmonary edema."

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